amino group
Definition
Noun: - The univalent chemical group -NH₂: A functional group in organic chemistry consisting of a nitrogen atom bonded to two hydrogen atoms. This group is basic in nature and is a key component of amino acids and many other organic compounds.
Usage
- As a subject: The amino group is essential for protein structure.
- As an object: This reaction replaces the hydrogen with an amino group.
- With a modifier: The primary amino group in glycine is reactive.
Examples
- The amino group (-NH₂) gives amino acids their basic properties.
- In this molecule, an amino group is attached to the carbon chain.
- The presence of an amino group is critical for the compound's biological activity.
Advanced Usage
- "Free amino group": Refers to an amino group that is not part of an amide or peptide bond and is therefore chemically reactive.
- The N-terminal residue of a peptide has a free amino group.
- "Primary amino group": Specifically denotes the -NH₂ group, as opposed to secondary (-NH-) or tertiary (=N-) amines.
- Methylamine contains a primary amino group.
Variants and Related Words
- Amino (adjective): Pertaining to or containing an amino group.
- Amino acids are the building blocks of proteins.
- Amine (noun): An organic compound derived from ammonia by replacement of one or more hydrogen atoms by organic groups. Amines contain the amino group as part of their structure.
- Methylamine is a simple amine.
Synonyms
- -NH₂ group: A direct synonym using the chemical formula.
- Amino radical: An equivalent term, especially in older chemical nomenclature.
Notes on Meaning
This term refers specifically to the -NH₂ functional group. It is distinct from the broader term "amine," which is a class of compounds containing this group. The amino group's ability to accept a proton (H⁺) makes it a basic site in organic molecules.
Noun
-
the radical -NH2
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